Original title: Způsob přípravy N - methylmorfolinoxidu
Title in English: A method for preparation of N-methylmorpholine-N-oxide…
First author: Prof. Josef Pašek, MSc, DSc
Short abstract:
A method for preparation of N-methylmorpholine-N-oxide through oxidation of N-methylmorpholine by an aqueous solution of hydrogen peroxide under temperature from 55 to 75°C and the molar ratio of H2O2:amine falling within 0.4 to 0.9, there is advantageous range from 0.5 to 0.7 here, at presence of chelating agents, or potentially, of carbon dioxide, and with unreacted portion of N-methylmorrpholine distilled off under reduced pressure.The method consits in addition of hydrazine at the amount equal to 0.01 to 0.05 wt%, based on the reaction mixture, when hydrogen peroxide is already added and its concentration in the reaction mixture dropped to 0.05 to 0.15 wt%. The reaction mixture is then left to react for a half an hour up to three hours.