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Obnovit | RAW

Analyte Determination in Medicine

Lecture Excercise/laboratory
2020, Summer Semester
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Credits 3
Hours per week 2 / 0 / 0
Examination Ex
Study Language Czech
Level []
Guarantor MUDr. Ivan Šebesta, CSc.

Summary

The aim of the subject is to obtain knowledge of the principles and possibilities of measurement of relevant diagnostic metabolites in clinical biochemistry, including the accuracy and quality control of analytical methods. In addition, students will learn to interpret important clinical biochemistry tests.

Syllabus

1.Determination of clinically significant ions in biological materials I
2.Determination of clinically significant ions in biological materials II
3.Determination of clinically significant substrates:glucose,other carbohydrates,glycated hemoglobin
4.Determination of acid-base balance
5.Total protein, albumin, aminoacids
6.Urea, creatinine,uric acid,nucleotides
7.Bilirubin, hemoglobin
8.Cholesterol, bile acids, triglycerides, lipoproteins
9.Determination of clinically significant enzymes I
10.Determination of clinically significant enzymes II
11.Biochemical tests in inborn errors of metabolism
12.Cardiac markers
13.Tumor markers
14.Drug monitoring, Amplichip

Literature

R:Schneiderka P. a kol., Kapitoly z klinické biochemie, Karolinum, 2004, 80-246-0678-X
R:Chromý V. a kol., Bioanalytika, analytická chemie v laboratorní medicíně, Masarykova univerzita Brno, 1992, 80-210-2917-X
R:Doležalová V. a kol., Principy biochemických vyšetřovacích metod.I a II.část, Institut pro další vzdělávání pracovníků ve zdravotnictví Brno,1995
A:Zima T. ed. Laboratorní diagnostika, druhé doplněné a přepracované vydání, Praha, Galén, 2007, 978-80-7262-372-3(Galén), 978-80-246-1423-6 (Karolinum)

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