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Obnovit | RAW

Hygienic and Clinical Microbiology

Lecture Excercise/laboratory
2019, Summer Semester
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Credits 3
Hours per week 2 / 0 / 0
Examination Ex
Study Language Czech
Level []
Guarantor doc. Ing. Pavel Ulbrich, Ph.D.

Summary

The course focuses on discrete groups of pathogenic microorganisms, the most important members of each group and their influence on human health. Students will also learn about the principles of antimicrobials and about the defence of microorganisms against these compounds. The attention will be paid to modern trends in protecting people against pathogens. On selected cases the mechanisms and prinicples of pathogenic microorganisms actions will be presented. In this course, students will also get acquainted with modern clinical microbiological laboratory methods.

Syllabus

1.History and importance of medical microbiology. Basic concepts associated with clinical microbiology. Cultivation media. Physiological flora, pathogenic and facultatively pathogenic microorganisms - a general overview.
2. Pathogenicity and virulence of bacteria. Routes of infection in the body, the adhesion of bacteria, tropism. Types of infections and their spread, the incubation period. Toxins, their distribution and function.
3. Antibiotics, classification, mechanisms of action, the emergence of resistance. Multiresistance. Spirochetes (Treponema, Leptospira, Borrelia).
4. Clinically significant Gram-positive cocci (Micrococcus, Staphylococcus, Streptococcus, Enterococcus), Gram-negative cocci and coccobacilli - Neisseria, etc. Gram-positive non-spore forming and sporulating aerobic rods (Listeria, Bacillus).
5. Anaerobic bacteria (important representatives of G+ and G- bacilli and cocci). Non Gram-dyeable bacteria (Mycobacterium, Nocardia). Mollicutes - representatives and diseases. Chlamydia - representatives and diseases.
6. Non spore-forming aerobic bacteria (Corynebacterium, Arcanobacter, Rhodococcus, Rothia). Gram-positive aerobic spore-forming rods - Clostridium. Aerobic gram-negative rods (Pseudomonas, Legionella, Chryseobacterium, Alcaligenes, Brucella, Francisella, Bordetella).
7. Facultative anaerobic gram-negative rods (Enterobacteriaceae). Gram-negative aerobic to microaerophilic rods (Helicobacter, Campylobacter). Rickettsia (Rickettsia, Coxiella, Ehrlichia, Rochalimaea, Bartonella).
8. Fungi - classification, epidemiology and diseases caused by fungi. Surface, subcutaneous and systemic mycoses.
9. General parasitology, protozoa. Parasitic annelids and arthropods.
10. Viruses - definition, history. The main groups of viruses, classification of viruses. Viral infection. Bacteriophages.
11. Selected representatives of animal DNA viruses (Poxviridae, Herpesviridae, Adenoviridae, Papovaviridae, Hepadnaviridae, Parvoviridae).
12. The most important representatives of RNA viruses (Orthomyxoviridae, Paramyxoviridae, Picornaviridae, Caliciviridae and Astroviridae, Reoviridae, Coronaviridae, Bunyaviridae, Togaviridae, Arenaviridae, Rhabdoviridae, Filoviridae, Retroviridae).
13. The causative agents of viral hepatitis. Prions and prion diseases.
14. Vaccination, vaccines, prinicples. Mandatory and recommended vaccinations.

Literature

R: M. Votava a kol., Lékařská mikrobiologie speciální, Neptun, Brno, 2003, 80-902896-6-5
A: M. Votava, Lékařská mikrobiologie obecná, Neptun, Brno, 2005, 80-86850-00-5
A: M. Votava a kol., Lékařská mikrobiologie vyšetřovací metody, Neptun, Brno, 2010, 978-80-86850-04-8

VŠCHT Praha
Technická 5
166 28 Praha 6 – Dejvice
IČO: 60461373
DIČ: CZ60461373

Datová schránka: sp4j9ch

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