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Obnovit | RAW

Forensic genetics

Lecture Excercise/laboratory
2020, Summer Semester
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Credits 5
Hours per week 2 / 2 / 0
Examination C+Ex
Study Language Czech
Level []
Guarantor Mgr. Halina Šimková
Supplemental electronic materials available at UCT Prague's e-learning

Summary

This course introduces students to the forensic DNA analysis as the dominant method of determining the origin of biological material. It describes biological principles on which the field is based, application circuits (criminology, kinship analysis, identification analysis, bioarcheology, recreational genetics), principles of analysis from the collection of biological material to final evaluation. It brings an overview of non-ID analysis and includes the basics of forensic statistics in the field of genetic analysis.

Syllabus

1. Introduction to forensic genetics, forensic genetics history, relationship to forensic biology and serology
2.Collection of biological traces and extraction of DNA from forensic samples
3.charakterization of DNA - DNA quantification, determination of quality and species specificity
4.Individuality as a complex concept, the principles of personal identification
5.Repetitive sequences of the human genome, STR markers
6.Methods of analysis on STR markers, the genetic profile analysis of composite samples
7.Forensic analysis of gonozomal markers and mitochondrial DNA
8.Population forensic genetics, forensic statistics
9.Non-human typing - forensic analysis of fauna and flora, forensic microbiology
10.Prediction of phenotype via DNA analysis and "non-ID" forensic DNA analysis
11.Forensic genetics laboratory, DNA databasing
12.Genogeography, genogenealogy, paleogenetics and biomolecular archaeology
13.Quality in the laboratory
14.Genetics as part of the forensic and investigative sciences and the Czech legal system

Literature

R:John M. Butler;Fundamentals of Forensic DNA Typing;Academic Press, 2009;9780123749994
R:John M. Butler;Advanced Topics in Forensic DNA Typing: Methodology;Academic Press,
2011;9780123745132
A:John M. Butler;Forensic DNA Typing, Second Edition: Biology, Technology, and Genetics of STR
Markers;Academic Press, 2005;9780121479527
A:Richard Li;Forensic Biology: Identification and DNA Analysis of Biological Evidence;CRC Press
2008;9781420043433
A:Ron C. Michaelis et al.;A Litigator's Guide to DNA:From the Laboratory to the Courtroom;Academic Press, 2008;9780123740366
A:N. Rudin, K. Inman;An Introduction to Forensic DNA Analysis, Second Edition;CRC Press
2001;9780849302336

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Copyright: UCT Prague
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